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bn:00003502n
Noun Concept
Categories: Articles with short description, Orphan drugs, Disease-modifying antirheumatic drugs, Nephrotoxins, Hepatotoxins
EN
methotrexate  methotrexate sodium  amethopterin  4-amino-10-methylfolic acid  4-amino-N(10)-methylpteroylglutamic acid
EN
Toxic antimetabolite that limits cellular reproduction by acting as an antagonist to folic acid; used to treat certain cancers and psoriasis and rheumatoid arthritis WordNet 3.0
Definitions
Relations
Sources
EN
Toxic antimetabolite that limits cellular reproduction by acting as an antagonist to folic acid; used to treat certain cancers and psoriasis and rheumatoid arthritis WordNet 3.0 & Open English WordNet
Methotrexate, formerly known as amethopterin, is a chemotherapy agent and immune-system suppressant. Wikipedia
A drug used to treat cancer and autoimmune diseases Wikipedia Disambiguation
Chemical compound Wikidata
IS A
antimetabolite
immunosuppressant
compound
medicine
essential medicines
FOUND IN TAXON
Gambierdiscus
MEDICAL CONDITION TREATED
acute myelocytic leukemia
ankylosing spondylitis
arthritis
rheumatoid arthritis
breast cancer
+29 relations
PHYSICALLY INTERACTS WITH
Folate transporter 1
proton-coupled folate transporter
PREGNANCY CATEGORY
Australian pregnancy category D
ROUTE OF ADMINISTRATION
intramuscular injection
intravenous drip
intrathecal
oral administration
SUBJECT HAS ROLE
vitamin Bc
immunosuppressant
antifolate
DNA polymerase inhibitors
disease-modifying antirheumatic drug
+2 relations
WordNet 3.0 & Open English WordNet
EN
methotrexate, methotrexate sodium, amethopterin
Wikipedia
EN
methotrexate
Wikidata
EN
methotrexate
Wikipedia Redirections
EN
Abitrexate, amethopterin, Antifolan, Arbitrexate, ATC code L01BA01, ATC code L04AX03, ATCvet code QL01BA01, ATCvet code QL04AX03, C20H22N8O5, Chexate, Ciptrexate, Emtexate, Jylamvo, Ledertrexate, Maxtrex, Metatrexan, Methatrixate, Methoblastin, Methotrate, Methotrexat, Methotrexate sodium, Methotrixate, Methrotrexate, Methyltrexate, Metoart, Metoject, Mexate, Nordimet, Rasuvo, Rheumatrex, Trexall
Wikidata Alias
EN
4-amino-10-methylfolic acid, Abitrexate®, Amethopterin, amethopterin, Methotrexat, Methotrexate, Methotrexatum, Metotrexato, MTX, Méthotrexate, Rasuvo®, 4-amino-N(10)-methylpteroylglutamic acid, N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic acid

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