Central New York is the central region of New York state, including: Auburn in Cayuga County Cortland in Cortland County Oneida in Madison County Syracuse, the largest city Central New York, in Onondaga County Fulton and Oswego in Oswego CountyWith a population of about 773,606 as of 2009 and an area of 3,715 square miles, the region includes the Syracuse metropolitan area. Wikipedia