In enzymology, a 12-hydroxydihydrochelirubine 12-O-methyltransferase is an enzyme that catalyzes the chemical reaction S-adenosyl-L-methionine + 12-hydroxydihydrochelirubine ⇌ {\displaystyle \rightleftharpoons } S-adenosyl-L-homocysteine + dihydromacarpineThus, the two substrates of this enzyme are S-adenosyl methionine and 12-hydroxydihydrochelirubine, whereas its two products are S-adenosylhomocysteine and dihydromacarpine. Wikipedia