In enzymology, an isoliquiritigenin 2'-O-methyltransferase is an enzyme that catalyzes the chemical reaction S-adenosyl-L-methionine + isoliquiritigenin ⇌ {\displaystyle \rightleftharpoons } S-adenosyl-L-homocysteine + 2'-O-methylisoliquiritigeninThus, the two substrates of this enzyme are S-adenosyl methionine and isoliquiritigenin, whereas its two products are S-adenosylhomocysteine and 2'-O-methylisoliquiritigenin. Wikipedia