A glutamyl-tRNA reductase is an enzyme that catalyzes the chemical reaction L-glutamate 1-semialdehyde + NADP+ + tRNAGlu ⇌ {\displaystyle \rightleftharpoons } L-glutamyl-tRNAGlu + NADPH + H+The 3 substrates of this enzyme are L-glutamate 1-semialdehyde, NADP+, and tRNA, whereas its 3 products are L-glutamyl-tRNA, NADPH, and H+. Wikipedia