In enzymology, a disulfoglucosamine-6-sulfatase is an enzyme that catalyzes the chemical reaction N,6-O-disulfo-D-glucosamine + H2O ⇌ {\displaystyle \rightleftharpoons } N-sulfo-D-glucosamine + sulfateThus, the two substrates of this enzyme are N,6-O-disulfo-D-glucosamine and H2O, whereas its two products are N-sulfo-D-glucosamine and sulfate. Wikipedia