In enzymology, 1-phosphofructokinase is an enzyme that catalyzes the chemical reaction ATP + D-fructose 1-phosphate → ADP + D-fructose 1,6-bisphosphateThus, the two substrates of this enzyme are ATP and D-fructose 1-phosphate, whereas its two products are ADP and D-fructose 1,6-bisphosphate. Wikipedia