Missouri, a state near the geographical center of the United States, has three distinct physiographic divisions: a north-western upland plain or prairie region part of the Interior Plains' Central Lowland known as the northern plains a lowland in the extreme southeast bootheel region of Missouri, part of the Atlantic Plain known as the Mississippi Alluvial Plain or the Mississippi embayment the Missouri portion of the Ozark Plateau which lies between the Mississippi Alluvial Plain and the Central lowland. Wikipedia