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bn:03648142n
Noun Concept
Categories: long volume value, EC 3.4, Alzheimer's disease, Integral membrane proteins, Protein complexes
EN
gamma secretase  gamma-secretase complex  gamma-secretase  TCDB:4.G.1  γ-secretase
EN
Gamma secretase is a multi-subunit protease complex, itself an integral membrane protein, that cleaves single-pass transmembrane proteins at residues within the transmembrane domain. Wikipedia
Definitions
Relations
Sources
EN
Gamma secretase is a multi-subunit protease complex, itself an integral membrane protein, that cleaves single-pass transmembrane proteins at residues within the transmembrane domain. Wikipedia
group of membrane-embedded proteases which cleave the transmembrane domains (TMSs) of type I membrane proteins Wikidata
A protein complex that has aspartic-type endopeptidase activity, and contains a catalytic subunit, presenilin (PS), that is a prototypical member of the GxGD-type aspartyl peptidases. The complex also contains additional subunits, including nicastrin Wikidata
IS A
cellular component
protein complex
aspartate protease
HAS PARTS OF THE CLASS
APH-1
Wikipedia
EN
gamma secretase
Wikidata
EN
gamma-secretase complex, gamma secretase
Wikipedia Redirections
EN
gamma-secretase
Wikidata Alias
EN
gamma-secretase, gamma secretase, GO:0070765, TCDB:4.G.1, γ-secretase, γ secretase

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