Santo is a masculine given name which may refer to: Santo Condorelli, Italian swimmer Santo Farina, of the rock and roll duo Santo & Johnny Santo Jeger, British politician Santo Loquasto, American production, set and costume designer Santo Mazzarino, Italian historian Santo Santoro, Australian politician Santo Stephens, American football player Santo Trafficante Jr., American Mafia boss, head of the Trafficante crime family Santo Trafficante Sr., Sicilian-born mobster, father of the above Santo Versace, Italian businessman and politician Wikipedia