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bn:17631344n
Noun Named Entity
Categories: Tyrosine kinase inhibitors, Mutation, EC 2.7 stubs
EN
V600E  BRAF V600E  BRAF V600  RS113488022  V640E
EN
V600E is a mutation of the BRAF gene in which valine is substituted by glutamic acid at amino acid 600. Wikipedia
Definitions
Relations
Sources
EN
V600E is a mutation of the BRAF gene in which valine is substituted by glutamic acid at amino acid 600. Wikipedia
IS A
missense mutation
PART OF
HT-29
CHROMOSOME
chromosome 7
NEGATIVE PROGNOSTIC PREDICTOR
colon cancer
melanoma
multiple myeloma
papillary thyroid cancer
NEGATIVE THERAPEUTIC PREDICTOR
cetuximab
oxaliplatin
irinotecan
vemurafenib
panitumumab
+1 relations
POSITIVE THERAPEUTIC PREDICTOR
vemurafenib
trametinib
dabrafenib
Wikipedia
EN
V600E
Wikidata
EN
BRAF V600E
Wikipedia Redirections
EN
BRAF V600
Wikidata Alias
EN
RS113488022, V600E, V640E, VAL600GLU, VAL640GLU

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